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Friday, May 25, 2012

Pediatric Appendicitis Score


Pediatric Appendicitis Score

(1 point) anorexia
(1 point) fever
(1 point) nausea/vomiting
(1 point) migration of pain
(2 points) pain with cough, percussion, or hopping
(2 points) RLQ tenderness
(1 point) Leukocytosis (WBC > 10,000)
(1 point) Left shift (ANC >6750)


  • 10 point scale incorporating history, physical and lab components
  • Initial study (Samuels, 2002) with N = 1170
  • Prospective cohort age 4-15 with abdominal pain suggestive of appendicitis
  • Cutoff of >=6 provides 1.00 sensitivity and 0.92 specificity
  • Logistic regression to determine best fit of diagnostic variables for sum of true-positive and true-negative results (total joint probability for a single cutoff)


  • Validation studies have shown better performance at the ends of the spectrum (using 2 cutoffs)
  • Validated prospectively and retrospectivelyIn ages > 1
  • Using various combinations of cutpoints
  • High risk scores (> 7) had a specificity of 95-98%
  • Low risk scores (<3) had a negative predictive value of 98%
  • Moderate risk scores indicated the need for further imaging
  • Use of the PAS would have decreased the need for imaging

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